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| Antigenic Specificity | UBE3A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100μg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC, IF, IP ? WB 1:500 - 1:2000; IHC 1:50 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-UBE3A polyclonal antibody. This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants ha |
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| Immunogen | ubiquitin protein ligase E3A |
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| Other Names | ANCR, AS, E6 AP, E6AP, E6AP ubiquitin protein ligase, EPVE6AP, FLJ26981, HPVE6A, UBE3A, ubiquitin protein ligase E3A |
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| Gene, Accession # | Gene ID: 7337, UniProt: Q05086 |
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| Catalog # | FNab09189 |
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| Price | |
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| Order / More Info | UBE3A Antibody from FINETEST |
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| Product Specific References | n/a |
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