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| Antigenic Specificity | DDB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100μg |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC, IP ? WB 1:500 - 1:1000; IHC 1:50 - 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-DDB1 polyclonal antibody. The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE) - an autosomal recessive disorder characterized by photosensitivity and early onset of carcinomas. However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the sam |
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| Immunogen | damage-specific DNA binding protein 1, 127kDa |
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| Other Names | XAP1 |
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| Gene, Accession # | Gene ID: 1642, UniProt: Q16531 |
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| Catalog # | FNab02284 |
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| Price | |
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| Order / More Info | DDB1 Antibody from FINETEST |
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| Product Specific References | n/a |
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