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| Antigenic Specificity | DKC1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100μg |
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| Concentration | n/a |
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| Applications | ELISA, WB ? WB 1:500 - 1:2000; IHC 1:50 - 1:200; IF 1:50 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit anti-DKC1 polyclonal antibody. This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. |
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| Immunogen | dyskeratosis congenita 1, dyskerin |
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| Other Names | NOLA4 |
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| Gene, Accession # | Gene ID: 1736, UniProt: O60832 |
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| Catalog # | FNab02400 |
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| Price | |
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| Order / More Info | DKC1 Antibody from FINETEST |
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| Product Specific References | n/a |
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