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產品名稱

TFPI, Human Antibody from HYCULT BIOTECH

產品貨號

HM2350

產品價格

現(xiàn)貨詢價，電話：010-67529703

產品規(guī)格

100 μg

產品品牌

HYCULT BIOTECH

產品概述

產品詳情

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Antigenic Specificity	TFPI, Human
Clone	C-terminus
Host Species	Mouse
Reactive Species	human
Isotype	IgG1
Format	unconjugated
Size	100 μg
Concentration	100 μg/ml
Applications	FC, immunoassay, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	TFPI is a serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI is known to interact and inhibit the activated factor X and VIIa-TF proteases in an autoregulatory loop. TFPI is a dual inhibitor, binding to the TF/FVIIa complex to prevent it from acting on its FIX and FX substrates, and by directly inhibiting FXa. Inadequate down-regulation of FXa function by TFPI deficiency leads to thrombosis. Besides coagulation, TFPI may play additional roles in innate immunity, microbial defense, inflammation, angiogenesis, lipid metabolism, and cellular signaling, proliferation, migration, and apoptosis.
Immunogen	Recombinant TFPI
Other Names	Tissue factor pathway inhibitor, Extrinsic pathway inhibitor
Gene, Accession #	n/a
Catalog #	HM2350
Price
Order / More Info	TFPI, Human Antibody from HYCULT BIOTECH
Product Specific References	n/a
產品資料

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