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        產(chǎn)品名稱 TLR10, Human Antibody from HYCULT BIOTECH
        產(chǎn)品貨號(hào) HM2302
        產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià),電話:010-67529703
        產(chǎn)品規(guī)格 100 μg
        產(chǎn)品品牌 HYCULT BIOTECH
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Antigenic SpecificityTLR10, Human
        Clone3C1C5
        Host SpeciesMouse
        Reactive Specieshuman
        IsotypeIgG1
        Formatunconjugated
        Size100 μg
        Concentration100 μg/ml
        ApplicationsFC, immunoassay
        Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
        DescriptionThe monoclonal antibody 3C10C5 reacts with human TLR-10, which is a type I transmembrane glycoprotein that consist of an extracellular domain, a single transmembrane segment and a cytoplasmic Toll/interleukin (IL)-1 receptor domain and has an apparent molecular mass of approximately 94kDa. In total humans possess 10 TLR family members (1-10). The TLR 10, 1, and 6 genes are tandemly arranged and seem to have arisen from duplication events. In accordance with their role in host defense, monocytes/macrophages express most TLRs, whereas the expression of individual TLRs in dendritic cells depends upon their subtype. The microbial agonists for TLRs include a wide variety of structures such as nucleic acids from bacteria and viruses, as well as outer membrane components of bacteria, fungi, and protozoan organisms. Despite extensive research on the TLRs, human TLR10 has remained an orphan receptor without a known agonist or function. Although recent studies have shown that the putative ligands include di- and triacetylated lipopeptides as can be found in bacteria. Variations in the TLR10 gene have been associated with several diseases such as papillary thyroid carcinoma, urothelial bladder cancer, and Crohn's disease. The monocalonal antibody 3C10C5 is suitable for immunoassay and flow cytometry.
        ImmunogenThe extracellular domain of TLR10
        Other NamesCD290
        Gene, Accession #n/a
        Catalog #HM2302
        Price
        Order / More InfoTLR10, Human Antibody from HYCULT BIOTECH
        Product Specific Referencesn/a
        產(chǎn)品資料
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