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產(chǎn)品名稱

TLR4, Human Antibody from HYCULT BIOTECH

產(chǎn)品貨號

HM2069

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

50 μg

產(chǎn)品品牌

HYCULT BIOTECH

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	TLR4, Human
Clone	HTA125
Host Species	Mouse
Reactive Species	human, canine, monkey
Isotype	IgG2a
Format	biotin conjugate
Size	50 μg
Concentration	100 μg/ml
Applications	IF, IP, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities, have been implicated in the innate host defense to pathogens. TLR4 has been identified next to MD-2 and CD14 as a receptor that is central to the innate immune response to lipopolysaccharides (LPS) of Gram-negative bacteria. The HTA125 monoclonal antibody reacts preferentially, especially in flow cytometry, with human TLR4 (CD284) that is associated with MD-2. HTA125 is a TLR4 (CD284) function-blocking antibody that is useful for studies on the role of TLR4 (CD284) as a receptor for LPS induced cytokine production by TLR4 bearing cells. The antibody was shown to precipitate TLR4 (100 kDa). The antibody HTA125 is cross reactive with canine, cynomolgus monkey, rhesus monkey and marmoset monkey.
Immunogen	BALB/c mice were immunized with the Ba/F3 line expressing TLR4
Other Names	TLR4, CD284, ARMD10
Gene, Accession #	n/a
Catalog #	HM2069
Price
Order / More Info	TLR4, Human Antibody from HYCULT BIOTECH
Product Specific References	n/a
產(chǎn)品資料

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