| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | Punctin-1, Human |
| Clone | 1B2-8-2 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 100 μg |
| Concentration | 100 μg/ml |
| Applications | immunoassay, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Monoclonal antibody 1B2-8-2 reacts with Punctin-1 (ADAMTSL-1). Punctin-1 is a secreted molecule resembling members of the family of proteases designated ADAMTS (a disintegrin-like and metalloprotease domain with thrombospondin type I motif). ADAMTS proteases are secreted enzymes that consist of a metalloprotease domain (which provides the catalytic activity) and ancillary domains (which provide substrate, cell or extracellular matrix activity). Punctin-1 lacks the pro-metalloprotease and the disintegrin-like domain typical of this family but contains other ADAMTS domains in precise order including 4 thrombospondin-I repeats. Punctin-1 is an extracellular matrix protein in tissues and deposited into the cell substratum and localized towards the periphery of transfected cells. Punctin-1 and Punctin-2 (ADAMTSL-3) are the first members of a novel family of ADAMTS-like proteins that appear to have important functions in the extracellular matrix. Monoclonal antibody 1B2-8-2 recognizes the first thrombospondin repeat near the N-terminal and reacts with molecular species of 55 kDa or a doublet of 55 k Da and 60 kDa (glycosylated form). Note that proteolysis of Punctin-1 has been described and additional smaller bands may also be obtained. |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | HM2169 |
| Price | |
| Order / More Info | Punctin-1, Human Antibody from HYCULT BIOTECH |
| Product Specific References | n/a |
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