| 產(chǎn)品詳情 |
| Edit |   |
| Product Name | LGK974 |
| Description | LGK-974 is a potent and specific inhibitor of Porcupine (porcn), a Wnt-specific acyltransferase (IC50 = ~0.4 nM). GK974 potently inhibits Wnt signaling, has strong efficacy in rodent tumor models, and is well-tolerated. In addition, head and neck cancer cell lines with loss-of-function mutations in the Notch signaling pathway have a high response rate to LGK974. MW: 396.44. Purity ≥98% by HPLC |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 2-(2',3-dimethyl-[2,4'-bipyridin]-5-yl)-N-(5-(pyrazin-2-yl)pyridin-2-yl)acetamide |
| Gene, Accession, CAS # | CAS: 1243244-14-5 |
| Catalog # | 2645-1 |
| Price | |
| Order / More Info | LGK974 from BIOVISION, INC. |
| Product Specific References | n/a |
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