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| Antigenic Specificity | NTB-A (NTBA) |
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| Clone | NT-7 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, cynomolgus |
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| Isotype | IgG1, κ |
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| Format | purified, azide-free |
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| Size | 500 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), Block, Stim |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | LEAF? Purified anti-human CD352 (NTB-A). NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases. |
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| Immunogen | Recombinant extracellular domain of NTB-A |
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| Other Names | SLAMF6, LY108, TCOM, SF2000, NTBA |
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| Gene, Accession # | Gene ID: 114836 |
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| Catalog # | 317204 |
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| Price | |
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| Order / More Info | NTB-A (NTBA) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 17513617,22156347 |
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