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產(chǎn)品名稱

SAHA (Vorinostat ) from ARBOR ASSAYS, INC.

產(chǎn)品貨號

P004-50MG

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

50 mg

產(chǎn)品品牌

ARBOR ASSAYS, INC.

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	SAHA (Vorinostat )
Description	SAHA (suberoylanilide hydroxamic acid, Vorinostat, Zolinza?) is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. Sirt activator based on a dihydropyridine structural scaffold. EC150 (effective concentration able to increase enzyme activity by 150%) is 1 uM for Sirt1, 25 uM for Sirt2, and 50 uM for Sirt3. The compound is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. SAHA inhibits class I and class II HDACs at around 50 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 uM.
Size	50 mg
Concentration	n/a
Applications	Activator or Inhibitor
Other Names	suberoylanilide hydroxamic acid, Vorinostat, Zolinza
Gene, Accession, CAS #	n/a
Catalog #	P004-50MG
Price
Order / More Info	SAHA (Vorinostat ) from ARBOR ASSAYS, INC.
Product Specific References	n/a
產(chǎn)品資料

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