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產(chǎn)品名稱

CD274 Antibody from BIOLEGEND

產(chǎn)品貨號

374513

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

25 tests

產(chǎn)品品牌

BIOLEGEND

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	CD274
Clone	MIH3
Host Species	Mouse
Reactive Species	human
Isotype	IgG1, κ
Format	allophycocyanin (APC) conjugate
Size	25 tests
Concentration	n/a
Applications	Flow Cytometry (FC)
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	APC anti-human CD274 (B7-H1, PD-L1). CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and non-hematopoietic cells.
Immunogen	Human PD-L1-transfected cells.
Other Names	Programmed cell death ligand 1 (PD-L1), B7 homolog 1 (B7-H1), B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
Gene, Accession #	Gene ID: 29126
Catalog #	374513
Price
Order / More Info	CD274 Antibody from BIOLEGEND
Product Specific References	n/a
產(chǎn)品資料

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