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| Antigenic Specificity | Human CD366 (Tim-3) |
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| Clone | F38-2E2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, κ |
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| Format | TotalSeq?-A oligomer conjugate |
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| Size | 10 μg |
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| Concentration | n/a |
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| Applications | PG |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TotalSeq?-A0169 anti-human CD366 (Tim-3). CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
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| Immunogen | Human Tim-3 fusion protein |
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| Other Names | T cell immunoglobulin and mucin domain containing protein 3, hepatitis virus cellular receptor 2, CD366 |
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| Gene, Accession # | Gene ID: 84868 |
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| Catalog # | 345047 |
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| Price | |
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| Order / More Info | Human CD366 (Tim-3) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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