| Description | Purity > 90% as determined by SDS-PAGE. MW: 47.4kDa. Full Length of Mature Protein: 19-269aa. N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Escherichia coli. Part of the tripartite complex that is required for the CDT activity. CdtB exhibits a DNA-nicking endonuclease activity, and very probably causes DNA damage in intoxicated cells. This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement. |
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