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產(chǎn)品名稱

Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) Antibody from ANTIBODIES-ONLINE GmbH

產(chǎn)品貨號(hào)

ABIN181553

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

50 μg

產(chǎn)品品牌

ANTIBODIES-ONLINE GmbH

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11)
Clone	polyclonal
Host Species	Goat
Reactive Species	human
Isotype	n/a
Format	biotin conjugate
Size	50 μg
Concentration	n/a
Applications	Enzyme Immunoassay (EIA),Western Blotting (WB)
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	RANKL is a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. There are three isoforms of RANKL. Human RANKL is a soluble 20 kDa polypeptide, comprising the TNF homologous region of RANKL (176 amino acid residues). This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor associated factor (TRAF) 6, which indicated that this protein may have a role in the regulation of cell apoptosis. RANKL deficient mice show severe osteoporesis and complete absence of osteoclasts as a result of lack of osteogenesis.Synonyms: ODF, OPGL, Osteoclast differentiation factor, Osteoprotegerin ligand, RANK Ligand, RANKL, Receptor activator of nuclear factor kappa B ligand, TNF-related activation-induced cytokine, TNFSF11, TRANCE, Tumor necrosis factor ligand superfamily member 11
Immunogen	Highly pure (> 98 %) recombinant human sRANKL
Other Names	TNFSF11\|BTF3L1\|HUMBTFB\|OCIF\|OPG\|TNFRSF11B\|CD254\|ODF\|OPGL\|OPTB2\|RANKL\|TRANCE\|hRANKL2\|sOdf\|Ly109l\|Trance\|Opg
Gene, Accession #	Gene ID: 8600
Catalog #	ABIN181553
Price
Order / More Info	Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific References	n/a
產(chǎn)品資料

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