| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | NIK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 μg |
| Concentration | 0.2 mg/ml |
| Applications | Western blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Polyclonal Antibody to detect NIK in Human, Mouse, Rat samples. NIK (NF-kB-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-kB activity. NIK was initially isolated from a human B cell cDNA library and contains 795 amino acids with an apparent molecular weight of slightly more than 97 kDa on SDS gel. NIK is a serine/threonine kinase and its kinase activity contributes to IkB phosphorylation. The carboxyl terminal segment of NIK binds TRAF2. A mutant NIK with intact carboxyl terminus but without the two lysine residues at its catalytic domain serves as a dominant-negative inhibitor for NF-kB activation. NIK also interacts with TRAF6 and mediates IL-1-induced NF-kB activation. |
| Immunogen | E. coli expressed recombinant human NIK fragment (a.a. 795-947). |
| Other Names | MAP3K14 |
| Gene, Accession # | Gene ID: 9020, Accession: Q99558 |
| Catalog # | 3193-100 |
| Price | |
| Order / More Info | NIK Antibody from BIOVISION, INC. |
| Product Specific References | n/a |
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