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產(chǎn)品名稱

OTUD7B Antibody from INVITROGEN ANTIBODIES

產(chǎn)品貨號(hào)

MA5-27168

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 μl

產(chǎn)品品牌

INVITROGEN ANTIBODIES

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	OTUD7B
Clone	OTI2E2
Host Species	Mouse
Reactive Species	human
Isotype	IgG1
Format	purified
Size	100 μl
Concentration	n/a
Applications	Western Blot: 1:500-1:2000
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	OTUD7B Monoclonal Antibody (OTI2E2). Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acting as a negative regulator of B-cell responses. In response to non-canonical NF- kappa-B stimuli, deubiquitinates 'Lys-48'-linked polyubiquitin chains of TRAF3, preventing TRAF3 proteolysis and over-activation of non-canonical NF-kappa-B. Negatively regulates mucosal immunity against infections. Mediates deubiquitination of EGFR. Has deubiquitinating activity toward 'Lys-11', 'Lys-48' or 'Lys-63'- linked polyubiquitin chains. In vitro, has preference for 'Lys- 11'-linked polyubiquitin chains; however such data are unsure in vivo. Hydrolyzes both
Immunogen	n/a
Other Names	OTU domain-containing protein 7B, Cellular zinc finger anti-NF-kappa-B protein, Zinc finger A20 domain-containing protein 1, Zinc finger protein Cezanne, OTUD7B, ZA20D1
Gene, Accession #	Entrez: 56957; Uniprot: Q6GQQ9
Catalog #	MA5-27168
Price
Order / More Info	OTUD7B Antibody from INVITROGEN ANTIBODIES
Product Specific References	n/a
產(chǎn)品資料

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