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        產(chǎn)品名稱 DuSP10, 149-482aa, Human, His tag, E.coli (Bioactivity Validated) from ATGen
        產(chǎn)品貨號(hào) ATGP1392
        產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià),電話:010-67529703
        產(chǎn)品規(guī)格 0.5mg, 100ug, 20ug
        產(chǎn)品品牌 ATGen
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Product NameDuSP10, 149-482aa, Human, His tag, E.coli (Bioactivity Validated)
        DescriptionPurity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 50% glycerol, 200mM NaCl. DuSP10 (Dual specificity protein phosphatase 10) belongs to the protein-tyrosine phosphatase family. Dual specificity protein phosphatases(DuSPs) inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. DuSP10 has been shown to interact with MAPK14 and MAPK8. When expressed in mammalian cells, DuSP10 blocks the enzymatic activation of MAP kinases with the selectivity p38 approximately JNK/SAPK >> ERK. Recombinant human DuSP10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
        Size0.5mg, 100ug, 20ug
        Concentrationn/a
        ApplicationsEnzyme activity
        Other NamesDual specificity protein phosphatase 10, MKP-5, MKP5
        Gene, Accession, CAS #NP 009138
        Catalog #ATGP1392
        Price
        Order / More InfoDuSP10, 149-482aa, Human, His tag, E.coli (Bioactivity Validated) from ATGen
        Product Specific Referencesn/a
        產(chǎn)品資料
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