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產(chǎn)品名稱

DuT, 70-252aa, Human, His tag, E.coli from ATGen

產(chǎn)品貨號

ATGP0725

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

0.5mg, 100ug, 20ug

產(chǎn)品品牌

ATGen

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	DuT, 70-252aa, Human, His tag, E.coli
Description	Purity: > 90 % by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl. . DuT, also known as duTP pyrophosphatase, is a ubiquitous enzyme that functions in nucleotide metabolism. This protein, in the presence of magnesium ions, is responsible for hydrolyzing duTP to duMP and diphosphate. This reaction is important for keeping the intracellular duTP concentration low so that uracil does not become incorporated into DNA. Extensive incorporation of uracil into DNA can ultimately lead to cell death. This suggests that DuT is essential for cell viability, further implying that it is a potential target for anticancer therapy. Recombinant human DuT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Size	0.5mg, 100ug, 20ug
Concentration	n/a
Applications	SDS-PAGE
Other Names	Deoxyuridine 5-triphosphate nucleotidohydrolase mitochondrial, duTPase, duTP pyrophosphatase, FLJ20622, Deoxyuridine 5-triphosphate nucleotidohydrolase mitochondrial, Deoxyuridine Triphosphatase
Gene, Accession, CAS #	NP 001020419
Catalog #	ATGP0725
Price
Order / More Info	DuT, 70-252aa, Human, His tag, E.coli from ATGen
Product Specific References	n/a
產(chǎn)品資料

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