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| Antigenic Specificity | CD123 |
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| Clone | 6H6 |
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| Host Species | Mouse |
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| Reactive Species | human, cross-reactivity: rhesus |
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| Isotype | IgG1, κ |
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| Format | Brilliant Violet 421? conjugate |
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| Size | 25 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Brilliant Violet 421? anti-human CD123. CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells. |
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| Immunogen | Human IL-3Rα transfected COS cells. |
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| Other Names | IL-3Rα, IL-3 Receptor alpha |
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| Gene, Accession # | Gene ID: 3563 |
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| Catalog # | 306017 |
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| Price | |
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| Order / More Info | CD123 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 20357241,20512127,25687283 |
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