| 產(chǎn)品詳情 |
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| Antigenic Specificity | DERP-1 |
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| Clone | H.AK5.C |
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| Host Species | Human |
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| Reactive Species | house dust mite |
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| Isotype | IgG1 k |
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| Format | purified |
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| Size | 100μg/50μg |
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| Concentration | n/a |
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| Applications | ELISA, WB, biopanning |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | House-dust mite allergy belongs to the most common allergies worldwide which affect more than 50% of all allergic patients. House dust mite allergens play an important role in inducing IgE-mediated sensitization and the development of bronchial hyper responsiveness and asthma, perennial rhinitis, and atopic dermatitis. Allergic patients' sera (IgE) recognize the house-dust mite Dermatophagoides pteronyssinus Der p 1 and Der p 2. The key event in these reactions is the cross-linking of IgE antibodies on effector cells by allergens, which induces a release of biologically active mediators like histamine and leukotrienes leading to different symptoms of allergy. Studies in vivo have shown that the cysteine peptidase activity of group 1 house dust mite allergens contributes to their allergenicity. (Chapman MD, 1980; J. Immunol., 125: 587-592; Hales BJ, Thomas WR., 1997; Clin. Exp. Allergy, 27(8):868- 875; Doull IJ. et al, 1997; Allergy, 52,220; Custovic A, 1996; J. Allergy Clin. Immunol., 98: 64-72; Szalai K. et al., 2008; Mol. Immunol. 45:5, 1308-17) |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | n/a |
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| Catalog # | DDX0212 |
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| Price | |
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| Order / More Info | DERP-1 Antibody from DENDRITICS SAS |
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| Product Specific References | n/a |
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