| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | HPA-5b |
| Clone | B4F12 |
| Host Species | Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | purified |
| Size | 100μg/50μg |
| Concentration | n/a |
| Applications | IF, ELISA, preferential detection of activated platelet by flow cytometry, platelet aggregation studies |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Neonatal AlloImmune Thrombocytopenia (NAIT) is the commonest cause of severe isolated thrombocytopenia in the foetus and newborn. In Caucasians, 97% of NAIT are caused by HPA-1a or HPA-5b alloantibodies. B4F12 was isolated after combination of CD40 activation and Epstein-Barr virus transformation of B cells isolated from a woman with high titre of anti -HPA-5b alloantibodies. B4F12 human monoclonal antibody recognizes GPIa-IIa preferentially on activated human platelets (Merieux Y, Rigal D, Pin JJ, XVIIth Regional Congress, International Society of Blood Transfusion, Madrid 2007 ; Guillot-Chene P, Lebecque S, Rigal D, Annales Pharmaceutiques Francaises, 06/2009, 67 (3) 182-6 |
| Immunogen | n/a |
| Other Names | GPIa-IIa |
| Gene, Accession # | n/a |
| Catalog # | DDX9022 |
| Price | |
| Order / More Info | HPA-5b Antibody from DENDRITICS SAS |
| Product Specific References | n/a |
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