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產(chǎn)品名稱

TLR10 Antibody from DENDRITICS SAS

產(chǎn)品貨號(hào)

DDX0490

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100μg/50μg

產(chǎn)品品牌

DENDRITICS SAS

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	TLR10
Clone	25F9
Host Species	Mouse
Reactive Species	human
Isotype	IgG1
Format	purified
Size	100μg/50μg
Concentration	n/a
Applications	FACS on transfected cells, IHC
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	The Toll-Like Receptors (TLR) is a family of germline-encoded proteins, composed of C-terminal leucine-rich repeats (LRR), and an N-terminal Toll/Interleukin-1 Receptor (TIR) domain (1). In humans, 10 TLRs, sharing high sequence homology, have been identified. TLRs are critical for the detection of pathogen-associated molecular patterns (PAMPs) by the innate immune system. LRR recognize PAMPs, and signal transduction events, initiated by the TIR domain, lead to activation of the transcription factors such as AP-1, IRFs and NFkB, and therefore expression of proinflammatory cytokines and costimulatory molecules.. TLR9 mRNA is detected in spleen, lymph nodes, bone marrow and PBLs (6, 7).Human TLR10 is an orphan member of the TLR family. Genomic studies indicate that TLR10 is in a locus that also contains TLR1 and TLR6, two receptors known to function as coreceptors for TLR2. (Akira, S et al, Nat Rev Immunol ,2004 4:499-511 ; Flacher V et al, J.Immunol, 2006,177, 959-67 ; Hasan U et al, J.Immunol, 2005, 174, 2942-50)
Immunogen	n/a
Other Names	Toll-like receptor 10
Gene, Accession #	n/a
Catalog #	DDX0490
Price
Order / More Info	TLR10 Antibody from DENDRITICS SAS
Product Specific References	n/a
產(chǎn)品資料

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