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| Antigenic Specificity | CD86 Molecule (CD86) |
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| Clone | GL1 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. 1-5 CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation. CD86, along with CD80/B7-1, is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152/CTLA-4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. |
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| Immunogen | LPS-activated mouse B cells 1 |
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| Other Names | B7-2|B7|B7.2|B70|CLS1|Cd28l2|ETC-1|Ly-58|Ly58|MB7|MB7-2|TS/A-2|CD28LG2|LAB72 |
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| Gene, Accession # | Gene ID: 12524 |
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| Catalog # | ABIN375402 |
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| Price | |
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| Order / More Info | CD86 Molecule (CD86) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 21889358 |
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