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| Antigenic Specificity | Chemokine (C-C Motif) Receptor 6 (CCR6) (aa 358-374), (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human CCR6(358-374aa RQTSETADNDNASSFTM), different from the related rat and mouse sequences by two amino acids. |
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| Other Names | BN-1|C-C CKR-6|CC-CKR-6|CCR-6|CD196|CKR-L3|CKRL3|CMKBR6|DCR2|DRY6|GPR29|GPRCY4|STRL22|Cmkbr6|KY411 |
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| Gene, Accession # | Gene ID: 1235,308163 |
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| Catalog # | ABIN343396 |
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| Price | |
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| Order / More Info | Chemokine (C-C Motif) Receptor 6 (CCR6) (aa 358-374), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 9070937, 10843722 |
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