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| Antigenic Specificity | Lysosomal-Associated Membrane Protein 1 (LAMP1) |
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| Clone | 1D4B |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | fluorescein (FITC) conjugate |
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| Size | 0.5 mg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. |
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| Immunogen | Plasma membrane fraction of mouse embryo NIH3T3 cell line1 |
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| Other Names | AI196048|CD107a|Lamp-1|LAMPA|LGP120|LEP100 |
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| Gene, Accession # | Gene ID: 16783 |
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| Catalog # | ABIN135443 |
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| Price | |
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| Order / More Info | Lysosomal-Associated Membrane Protein 1 (LAMP1) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 3923938, 8647888 |
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