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| Antigenic Specificity | Selectin L (SELL) |
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| Clone | OX-85 |
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| Host Species | Mouse |
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| Reactive Species | rat |
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| Isotype | IgG1 |
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| Format | ion exchange chromatography purified |
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| Size | 250 μg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS),ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | purified anti-rat CD62L monoclonal antibody recognizes rat leukocyte selectin (L-selectin). CD62L is expressed constitutively on leukocytes and is expressed by a subset of thymocytes predominantly single positive CD4 or CD8 cells and a majority of lymph node cells in rats. CD62L binds well to O-glycans present on certain glycoforms of the mucins GlyCAM-1, CD34 and MAdCAM-1. CD62L is reported to be capable of capable of transducing signals when cross- linked and has been shown to stimulate -integrin-mediated adhesion when bound to soluble GlyCAM-1. [1] L-selectin expressing CD4 CD8 thymocytes were shown through adoptive transfer to protect rats from insulin-dependent diabetes. CD4 CD8 thymocytes must mature to the stage of L-selectin expression before they can mediate normal T cell function. [2] Sensitive detection systems may be required on some tissues as expression of rat CD62L is weak. |
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| Immunogen | Recombinant rat L-selectin . Fusion Partner: NSI/1 . Donor: BALB/c Spleen |
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| Other Names | CD62L|LAM1|LECAM1|LEU8|LNHR|LSEL|LYAM1|PLNHR|TQ1|A.11|L-selectin|LECAM-1|SELE|AI528707|Lnhr|Ly-22|Ly-m22|Lyam-1|Lyam1 |
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| Gene, Accession # | Gene ID: 20343,6402,29259,100009204,100716722,480080,100127147,281485,701419,450191 |
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| Catalog # | ABIN133421 |
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| Price | |
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| Order / More Info | Selectin L (SELL) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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