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| Antigenic Specificity | Integrin-Binding Sialoprotein (IBSP) (aa 305-324), (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IBSP(integrin-binding sialoprotein) is also known as BSP. The protein encoded by this gene is a major structural protein of the bone matrix. Bone sialoprotein is an acidic glycoprotein of approximately 70 kD that undergoes extensive posttranslational modifications. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. The BSP gene is mapped to 4q22.1. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bone Sialoprotein(305-324aa SYYKGHGYEGYEGQNYYYHQ), different from the related rat sequence by one amino acid. |
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| Other Names | IBSP|Aa2-066|pp63|BSP|BSP II|BSPII|Bsp2|BNSP|BSP-II|SP-II|Bsp|2AR|Apl-1|BSPI|ETA-1|Eta|OP|Opn|Opnl|Ric|Spp-1 |
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| Gene, Accession # | Gene ID: 15891,24477 |
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| Catalog # | ABIN1673366 |
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| Price | |
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| Order / More Info | Integrin-Binding Sialoprotein (IBSP) (aa 305-324), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 21533022, 19492334 |
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