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| Antigenic Specificity | beta-Site APP-Cleaving Enzyme 2 (BACE2) (Middle Region) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 μg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. |
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| Immunogen | BACE2 antibody was raised using the middle region of BACE2 corresponding to a region with amino acids SLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGF |
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| Other Names | AEPLC|ALP56|ASP1|ASP21|BAE2|CEAP1|DRAP|1110059C24Rik|AI850424|ARP1|CDA13 |
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| Gene, Accession # | Gene ID: 25825 |
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| Catalog # | ABIN635132 |
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| Price | |
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| Order / More Info | beta-Site APP-Cleaving Enzyme 2 (BACE2) (Middle Region) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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