| 產(chǎn)品詳情 |
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| Antigenic Specificity | Phospho-CCR5(Ser349) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 μl |
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| Concentration | 1mg/ml |
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| Applications | Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blotting, ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Polyclonal antibody to detect Phospho-CCR5(Ser349). CCR5 a 7-transmembrane G-linked receptor for a number of inflammatory C-C type chemokines including MIP-1-alpha, MIP-1-beta and RANTES. Transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (along with CD4) for HIV-1 R5 isolates. Interacts with PRAF2. Interacts with HIV-1 surface protein gp120. Efficient ligand binding to CCL3/MIP-1alpha and CCR4/MIP-1beta requires sulfation, Oglycosylation and sialic acid modifications. Glycosylation on S6 is required for efficient binding of CCL4. |
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| Immunogen | A synthesized peptide derived from human CCR5 around the phosphorylation site of Sersine 349. |
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| Other Names | AM4 7, C-C chemokine receptor type 5, CC CKR 5, CCR 5, CD 195, Chemokine receptor CCR5, CHEMR13, CKR 5, CMKBR 5, FLJ78003, HIV1 fusion coreceptor, IDDM22, MIP-1 alpha receptor |
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| Gene, Accession # | Gene ID: 1234, Accession: P51681 |
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| Catalog # | A1734-100 |
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| Price | |
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| Order / More Info | Phospho-CCR5(Ser349) Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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