| Edit |   |
|---|
| Antigenic Specificity | LOXL2 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, rat, mouse |
|---|
| Isotype | n/a |
|---|
| Format | unconjugated |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | WB, IHC |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Rabbit Anti-Human LOXL2 polyclonal antibody for WB, IHC. Lysyl oxidase homolog 2 (EC1.4.3.13; also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, or Lysyl oxidase-related protein WS9-14) is encoded by the LOXL2 gene (also known as LOR2 or WS9-14) in human. LOXL2 protein catalyzes oxidative deamination of target lysine residues to allysine. Secreted LOXL2 protein mediates cross-linking of extracellular matrix proteins by targeting lysine residues in fibrous collagen and elastin in precursors. It is also found in the nucleus where it acts as a transcription corepressor by targeting trimethylated histone H3 Lys3 (H3K4me3). Its involvement in other biological processes inclucdes epithelial to mesenchymal transition (EMT) and repression of E-cadherin expression. |
|---|
| Immunogen | Recombinant Protein |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | Gene ID: 4017, UniProt: Q9Y4K0 |
|---|
| Catalog # | CABT-B1580 |
|---|
| Price | |
|---|
| Order / More Info | LOXL2 Antibody from CREATIVE DIAGNOSTICS |
|---|
| Product Specific References | n/a |
|---|