欧美顶级毛,国产aV一区二区三区线,久久综合伊人777777,国产青娱乐在线视频,在线不卡视频,尤物视频免费观看,99精品无码,av黄色大片

<button id="eiezk"><video id="eiezk"></video></button>

產(chǎn)品名稱

JAM-A, Human Antibody from HYCULT BIOTECH

產(chǎn)品貨號(hào)

HM2098F

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

HYCULT BIOTECH

產(chǎn)品概述

產(chǎn)品詳情

Edit	&nbsp
Antigenic Specificity	JAM-A, Human
Clone	BV16
Host Species	Mouse
Reactive Species	human
Isotype	IgG1
Format	fluorescein (FITC) conjugate
Size	100 μg
Concentration	100 μg/ml
Applications	frozen sections, FC, functional studies, IF, IP, paraffin sections, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	The FITC conjugated monoclonal antibody BV16 recognizes the human junction adhesion molecule (JAM)-A. Together with JAM-C (JAM-2) and JAM-B (VE-JAM or JAM-3), JAM-A belongs to a family of adhesion proteins with a V-C2 immunoglobulin domain organization and their molecular weight is about 30-40 kDa. JAMs are important for a variety of cellular processes, including tight junction assembly, leukocyte transmigration, platelet activation, angiogenesis and virus binding. JAM-A is expressed by endothelial and epithelial cells, platelets, neutrophils, monocytes, lymphocytes and erythrocytes. Like all other JAMs, JAM-A plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. JAM-A also plays an important role in leukocyte transmigration. Leukocyte transmigration can be blocked by antibodies and by soluble JAM-A/Fc fusion proteins. Homophilic JAM-A interactions between leukocytes and the endothelium but also heterophilic interactions of JAM-A with the beta 2-integrin leukocyte function-associated antigen-1 (LFA-1) are considered to actively guide leukocytes during transmigration. Several studies imply a role for JAM-A in the initiation of atherosclerosis, since JAM-A is upregulated on early atherosclerotic endothelium. Adhesion of the activated platelets on activated endothelium is mediated by homophilic interactions of JAM-A.
Immunogen	Fusion protein consisting of the extracellular domain of human JAM and the Fc portion of human IgGs
Other Names	PAM-1, JAM-1, JAMA, CD321, platelet F11 receptor
Gene, Accession #	n/a
Catalog #	HM2098F
Price
Order / More Info	JAM-A, Human Antibody from HYCULT BIOTECH
Product Specific References	n/a
產(chǎn)品資料

<button id="eiezk"><video id="eiezk"></video></button>