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        產(chǎn)品名稱 Plasminogen Activator, Tissue (PLAT) (AA 36-562) protein (His tag) from ANTIBODIES-ONLINE GmbH
        產(chǎn)品貨號 ABIN1691743
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格 10 μg
        產(chǎn)品品牌 ANTIBODIES-ONLINE GmbH
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Product NamePlasminogen Activator, Tissue (PLAT) (AA 36-562) protein (His tag)
        DescriptionTissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and peptidase S1 domain. It belongs to the peptidase S1 family. The main function of this protein is to convert plasminogen into biologically active plasmin. As a protease, PLAT plays a crucial role in regulating blood fibrinolysis, maintaining the homeostasis of extracellular matrix and in modulating the post-translational activation of growth factors. PLAT is found not only in the blood, where its primary function is as a thrombolytic enzyme, but also in the central nervous system (CNS). It participates in a number of physiological and pathological events in the CNS, as well as the role of neuroserpin as the natural regulator of PLAT's activity in these processes. Increased or decreased activity of PLAT leads to hyperfibrinolysis or hypofibrinolysis, respectively. In addition, as a cytokine, PLAT plays a pivotal role in the pathogenesis of renal interstitial fibrosis through diverse mechanisms. Thus, as a fibrogenic cytokine, it promotes the progression of kidney diseases.Alternative Names: T-PA, TPA, t-plasminogen activator, Tissue plasminogen activator,
        Size10 μg
        Concentrationn/a
        Applicationsn/a
        Other Namestpa|Plat|T-PA|TPA|AU020998|AW212668|D8Ertd2e|tPA|PATISS
        Gene, Accession, CAS #Gene ID: 5327
        Catalog #ABIN1691743
        Price
        Order / More InfoPlasminogen Activator, Tissue (PLAT) (AA 36-562) protein (His tag) from ANTIBODIES-ONLINE GmbH
        Product Specific Referencesn/a
        產(chǎn)品資料
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