| 產(chǎn)品詳情 |
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| Antigenic Specificity | DKK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 μg |
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| Concentration | 0.5 mg/ml |
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| Applications | Western blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DKK1 Antibody. Xenopus Dickkopf (Dkk)-1 was initially discovered as a Wnt antagonist that plays an important role in head formation. By far, four members of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domains. Recent studies showed that the second Cys-rich domains of Dkk1 and Dkk2 inhibited Wnt-3a-activated signaling, whereas the first Cys-rich domains had no effects. In addition, the second Cys-rich domain of Dkk-2, but not that of Dkk-1, was able to activate the canonical pathway in the presence of LRP6, and this LRP-dependent signaling does not require Dvl. |
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| Immunogen | Synthetic peptide surrounding amino acid 255 of mouse Dkk1 |
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| Other Names | DKK-1 , DKK1 , SK , dickkopf homolog 1 , dickkopf-1 , dickkopf-1 like |
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| Gene, Accession # | Gene ID: 13380, Accession: O54908 |
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| Catalog # | 3851-100 |
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| Price | |
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| Order / More Info | DKK1 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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