| 產(chǎn)品詳情 |
| Edit |   |
| Antigenic Specificity | DKK2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 μg |
| Concentration | 0.5 mg/ml |
| Applications | Western blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | DKK2 Antibody. Xenopus Dickkopf (Dkk)-1 was initially discovered as a Wnt antagonist that plays an important role in head formation. By far, four members of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domains. Recent studies showed that the second Cys-rich domains of Dkk1 and Dkk2 inhibited Wnt-3a-activated signaling, whereas the first Cys-rich domains had no effects. In addition, the second Cys-rich domain of Dkk-2, but not that of Dkk-1, was able to activate the canonical pathway in the presence of LRP6, and this LRP-dependent signaling does not require Dvl. |
| Immunogen | Synthetic peptide surrounding amino acid 241 of mouse Dkk2 |
| Other Names | DKK-2, DKK 2, dkk2, dkk-2, dkk 2, dickkopf homolog-2, dickkopf homolog2, dickkopf homolog 2 |
| Gene, Accession # | Gene ID: 56811, Accession: NP_064661.2 |
| Catalog # | 3802R-100 |
| Price | |
| Order / More Info | DKK2 Antibody from BIOVISION, INC. |
| Product Specific References | n/a |
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