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產(chǎn)品名稱

MAD2 Antibody from BIOVISION, INC.

產(chǎn)品貨號(hào)

3766-100

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 μl

產(chǎn)品品牌

BIOVISION, INC.

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	MAD2
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human
Isotype	n/a
Format	affinity purified
Size	100 μl
Concentration	n/a
Applications	Western blot, Immunoprecipitation
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	MAD2 Antibody. Cell cycle progression is subject to arrest at the mitotic spindle assembly checkpoint in response to incorrect spindle fiber assembly. MAD2 (for mitotic arrest-deficient) is a component of the mitotic spindle checkpoint. Cells with mutated MAD2 do not undergo mitotic arrest in response to incorrect spindle fiber assembly, which results in missegregation and eventual cell death. A breast carcinoma cell line with reduced MAD2 expression, T47D, was shown to complete mitosis in the presence of nocodazole, an inhibitor of mitotic spindle assembly. MAD2 is localized to unattached kinetochores during prometaphase and disassociates upon spindle fiber attachment, indicating that MAD2 regulates kinetochore binding to the spindle fiber
Immunogen	Synthetic peptide of human MAD2
Other Names	MAD2, HsMAD2, Mitotic Arrest Deficient 2, MAD2L1, MAD2-like 1
Gene, Accession #	Gene ID: 4085, Accession: Q13257
Catalog #	3766-100
Price
Order / More Info	MAD2 Antibody from BIOVISION, INC.
Product Specific References	n/a
產(chǎn)品資料

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