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        產(chǎn)品名稱 Recombinant Mouse IL-13 (carrier-free) from BIOLEGEND
        產(chǎn)品貨號 575904
        產(chǎn)品價格 現(xiàn)貨詢價,電話:010-67529703
        產(chǎn)品規(guī)格 25 μg
        產(chǎn)品品牌 BIOLEGEND
        產(chǎn)品概述
        產(chǎn)品詳情
        Edit&nbsp
        Product NameRecombinant Mouse IL-13 (carrier-free)
        DescriptionMouse IL-13 was initially cloned from cDNA libraries of activated T cells and was designated as P600. IL-13 is an immunoregulatory cytokine secreted predominantly by activated T(H)2 cells, and it is a key mediator in the pathogenesis of allergic inflammation. IL-13 shares many functional properties with IL-4, and they share a common receptor subunit, the alpha subunit of the IL-4 receptor (IL-4Ralpha). IL-13 mediates its effects by interacting with a complex receptor system comprised of IL-4Ralpha and two IL-13 binding proteins, IL-13Ralpha1 and IL-13Ralpha2. Ligation of the IL-13 receptor complex results in signaling via the insulin receptor substrate (IRS)-1 and 2 and STAT-6 pathways. Interleukin-13 (IL-13), like IL-4, is a cytokine produced by T(H)2 type helper T cells in response to signaling through the T cell antigen receptor and by mast cells and basophils upon cross-linkage of the high-affinity receptor for immunoglobulin E (IgE). IL-13 has been implicated in airway hypersensitivity and mucus hypersecretion, inflammatory bowel disease, and parasitic nematode expulsion.
        Size25 μg
        Concentrationn/a
        ApplicationsBA
        Other NamesInterleukin-13, NC30
        Gene, Accession, CAS #Gene ID: 16163
        Catalog #575904
        Price
        Order / More InfoRecombinant Mouse IL-13 (carrier-free) from BIOLEGEND
        Product Specific Referencesn/a
        產(chǎn)品資料
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