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產(chǎn)品名稱(chēng)

ONO AE3 208 from TOCRIS BIOSCIENCE

產(chǎn)品貨號(hào)

3565/10

產(chǎn)品價(jià)格

現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703

產(chǎn)品規(guī)格

10 mg

產(chǎn)品品牌

TOCRIS BIOSCIENCE

產(chǎn)品概述

產(chǎn)品詳情

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Product Name	ONO AE3 208
Description	High affinity and selective EP4 receptor antagonist (Ki values are 1.3, 30, 790 and 2400 nM for EP4, EP3, FP and TP receptors respectively). Displays no affinity for EP1, EP2, DP or IP receptors (Ki >10 μM). Inhibits PGE2-induced IL-8 production in colonic epithelial caco-2 cells and attenuates PGE2 inhibition of natural killer T cell activation. Suppresses recovery from experimentally-induced colitis and stimulates CD4+ T cell proliferation in C57BL/6 mice. Also reduces metastasis of mammary tumor cells in a murine model of breast cancer. Orally active. Purity 98%. MW (observed): 404.43
Size	10 mg
Concentration	n/a
Applications	n/a
Other Names	4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]benzenebutanoic acid
Gene, Accession, CAS #	CAS: 402473-54-5
Catalog #	3565/10
Price
Order / More Info	ONO AE3 208 from TOCRIS BIOSCIENCE
Product Specific References	n/a
產(chǎn)品資料

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