| 產品詳情 |
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| Product Name | PQ 69 |
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| Description | Potent and selective A1 receptor inverse agonist. Exhibits high binding affinity at A1 receptor (Ki values are 0.07 and 0.96 nM for rat and human receptors respectively). Reduces basal [35S]-GTPγS binding 44.6% (IC50 = 0.19 nM). Antagonizes the effects of A1 agonist R-PIA (IC50 = 18.3 nM) and exhibits competitive antagonism on CCPA -induced tracheal contractions ex vivo. Displays 217- fold selectively over hA2A receptor and >1000-fold selectivity over hA3 receptor. Purity 98%. MW (observed): 350.39 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-(Butylamino)-2-(3-fluorophenyl)-1,2-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one |
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| Gene, Accession, CAS # | CAS: 910045-32-8 |
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| Catalog # | 5351/10 |
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| Price | |
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| Order / More Info | PQ 69 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 產品資料 |
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