| Description | Antigen: recombinant full-length human caspase-3 ? Host: mouse, clone 31A1067? Isotype: IgG1κ ? Cross Reactivity: (+) human, mouse, and rat caspase-3 ? Application(s): IHC (frozen and paraffin-embedded sections) and WB ? Caspase-3 cleaves the death substrate PARP to a specific 85 kDa form observed during apoptosis and is inhibitable by the CrmA protein. Other caspase-3 substrates include DNA-PK, actin, GAS2, procaspase-6, etc. |
|---|