| Description | Antigen: human caspase-9 amino acids 299-318 ? Host: rabbit ? Application(s): WB ? Caspase-9 is activated by granzyme B, CPP32, or by binding Apaf-1. Activated caspase-9 cleaves and activates caspase-3, playing a central role in cell death induced by a wide variety of apoptosis inducers including TNF-α, TRAIL, anti-CD95, FADD, and TRADD. |