| 產(chǎn)品詳情 |
| Edit |   |
|---|
| Antigenic Specificity | ASGPR/CD301 |
|---|
| Clone | 125A10.03 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, dog |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100μg/50μg |
|---|
| Concentration | n/a |
|---|
| Applications | IHC, FACS surface, WB, antigen capture endocytosis |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | ASGPR/MGL (asialoglycoprotein / macrophage galactose lectin receptor) / CD301 is a Ca(2+)-dependent type II transmembrane lectin. Immunoprecipitation from DCs using anti-DC-ASGPR mAb yields a major 40-kDa protein. ASGPR mRNA is observed predominantly in immune tissues (DCs and granulocytes), but not in T, B, or NK cells, or monocytes. ASGPR species are restricted to the CD14-derived DCs obtained from CD34(+) progenitors, while absent from the CD1a-derived subset. Accordingly, both monocyte-derived DCs and tonsillar interstitial-type DCs express ASGPR protein, while Langerhans-type cells do not. ASGPR is a feature of immaturity, as expression is lost upon CD40L activation. In agreement with the presence of tyrosine-based and dileucine motifs in the intracytoplasmic domain, mAb against DC-ASGPR is rapidly internalized by DCs at 37 degrees C. Finally, intracellular ASGPR is localized in early endosomes, suggesting that the receptor recycles to the cell surface following internalization of ligand. ASGPR/HML is a feature of immature DCs and a subtype of macrophages, and likely important for the specialized antigen-capture function of DCs.(Valladeau J et al, 2001 J. Immunol.,167: 5767) |
|---|
| Immunogen | n/a |
|---|
| Other Names | ASGPR/MGL (asialoglycoprotein / macrophage galactose lectin receptor) |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | DDX0010 |
|---|
| Price | |
|---|
| Order / More Info | ASGPR/CD301 Antibody from DENDRITICS SAS |
|---|
| Product Specific References | n/a |
|---|
| 產(chǎn)品資料 |
|
天天操操操操,国产无毛在线观看,www.papapa
|
欧美99在线,小嫩逼视频,wkkcc久久
|
欧美操逼免费,艹逼网址,亚洲A∨无码无在线观看
|
aaa的视频,国产午夜福利视频一区二区在线,在线国内自拍
|
亚州中文字幕,sao货水真多把你cao烂69视频,一级免费网站
|
精品一品AV三级片,疯狂做爰呻吟声,歪歪动漫
|
人人操在线观看,成人网址在线观看,一区二区三区日韩
|
日本3级网站,美女被鬼压床脱内衣内裤视频,久久久性爱视频
|
国产666高清无码精品导航,日本AⅤ在线,在线观看免费毛片
|
天天操天天爱天天爽,99re这里只有,av久操
|
|