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產(chǎn)品名稱

PARP Antibody from BIOVISION, INC.

產(chǎn)品貨號(hào)

3140-100

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100 μg

產(chǎn)品品牌

BIOVISION, INC.

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	PARP
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human
Isotype	n/a
Format	affinity purified
Size	100 μg
Concentration	0.2 mg/ml
Applications	Western blot, Immunohistochemistry
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	PARP (Cleaved) Antibody. PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, is a highly conserved nuclear enzyme implicated in DNA repair and in the apoptosis response of cells. This protein can be cleaved by many caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. The cleavage occurs between ASP214 and Gly 215, which separates PARP's N-terminal DNA binding domain (24 kDa) from its C-terminal catalytic domain (89 kDa). It has been shown that cleavage of PARP facilitates cellular disassembly and inhibition of PARP cleavage attenuates apoptosis in vitro.
Immunogen	Synthetic peptide correspond to the N-terminal residues of the catalytic domain of human PARP
Other Names	PARP1, ADPRT, PPOL, NAD(+) ADP-ribosyltransferase 1
Gene, Accession #	Gene ID: 142, Accession: NP_001609
Catalog #	3140-100
Price
Order / More Info	PARP Antibody from BIOVISION, INC.
Product Specific References	n/a
產(chǎn)品資料

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