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產(chǎn)品名稱

MRP2/ABCC2 Antibody from BOSTER BIO

產(chǎn)品貨號(hào)

A00974-1

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

100ug

產(chǎn)品品牌

BOSTER BIO

產(chǎn)品概述

產(chǎn)品詳情

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Antigenic Specificity	MRP2/ABCC2
Clone	polyclonal
Host Species	Rabbit
Reactive Species	human, mouse, rat
Isotype	n/a
Format	immunogen affinity purified
Size	100ug
Concentration	500ug/ml.
Applications	IHC-P, WB
Reviews / Ratings	If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description	Rabbit IgG polyclonal Picoband? antibody for MRP2/ABCC2 detection. Tested with WB, IHC-P in Human;Mouse;Rat. No cross reactivity with other proteins. Multidrug resistance-associated protein 2 (MRP2), also called canalicular multispecific organic anion transporter 1 (cMOAT) or ATP-binding cassette sub-family C member 2 (ABCC2), is a protein that in humans is encoded by the ABCC2 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.
Immunogen	A synthetic peptide corresponding to a sequence of human MRP2/ABCC2(AIRHDCNFDKAMQFSEASFTWEHDSEATVRDVNLD).
Other Names	Canalicular multispecific organic anion transporter 1; ATP-binding cassette sub-family C member 2; Canalicular multidrug resistance protein; Multidrug resistance-associated protein 2; ABCC2; CMOAT; CMOAT1; CMRP; MRP2
Gene, Accession #	ABCC2, UniProt: Q92887
Catalog #	A00974-1
Price
Order / More Info	MRP2/ABCC2 Antibody from BOSTER BIO
Product Specific References	n/a
產(chǎn)品資料

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