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        加拿大cellscale生物組織材料機(jī)械力te性測(cè)試分析儀

        型號(hào):內(nèi)詳
        價(jià)格:請(qǐng)致電:010-67529703
        品牌:cellscale

        CellScale的生物反應(yīng)器為細(xì)胞和組織及其它材料對(duì)機(jī)械刺激的反應(yīng)提供了深入的洞察。cellscale系統(tǒng)針對(duì)高通量、實(shí)時(shí)成像、3D支架使用和多模式刺激進(jìn)行了化。CellScale在開(kāi)發(fā)定制解決方案方面擁有豐富的經(jīng)驗(yàn),效果屢超客戶(hù)預(yù)期。

        機(jī)械測(cè)試系統(tǒng)。

        在CellScale,我們的測(cè)試系統(tǒng)從頭到尾進(jìn)行了化,以表征生物材料的力學(xué)性能。環(huán)境艙和成像實(shí)現(xiàn)了完整的系統(tǒng)功能,省去了后顧之憂(yōu)。 能滿(mǎn)足從微尺度壓縮到雙軸拉伸的需求,CellScale的系統(tǒng)能提供值得信賴(lài)的尖端數(shù)據(jù)。



        一、BioTester雙軸材料

        專(zhuān)為生物材料而打造的一套設(shè)備齊的雙軸測(cè)試系統(tǒng)

        由于其定向取向的微觀結(jié)構(gòu),雙軸測(cè)試對(duì)于理解生物材料的機(jī)械性能而言是至關(guān)重要的。BioTester系統(tǒng)的設(shè)計(jì)使雙軸測(cè)試變得簡(jiǎn)單,使用戶(hù)可以專(zhuān)注于結(jié)果而不是測(cè)試本身。

        主要?jiǎng)?

        • 4個(gè)高性能的執(zhí)行機(jī)構(gòu),帶有直列加載傳感器
        • 使用基于圖像應(yīng)變測(cè)量工具的高分辨率CCD成像
        • 包括專(zhuān)利BioRakes在內(nèi)的多種附著選項(xiàng),可快速可靠地安裝樣品
        • 集成溫控介質(zhì)浴
        • 功能齊的用戶(hù)界面軟件,可進(jìn)行實(shí)時(shí)反饋的簡(jiǎn)單、循環(huán)、松弛和多模式測(cè)試


        試樣和安裝

        BioRake樣品安裝系統(tǒng)使用了CellScale專(zhuān)利技術(shù)的附著軟組織和生物材料的方法。

        每根尖齒都經(jīng)過(guò)電化學(xué)銳化,可以輕松刺穿硬和脆弱的組織樣本。每套都永久性地連接到一個(gè)共同的基座,可以同時(shí)刺穿鎖有20個(gè)連接點(diǎn)。磁力安裝的BioRakes便于清潔或更換,可以實(shí)現(xiàn)BioRake、平衡滑輪和夾具安裝系統(tǒng)之間的輕松轉(zhuǎn)換。

        進(jìn)行測(cè)試時(shí),使用手動(dòng)升降機(jī)構(gòu)將樣本定位并升高到位,并施加壓力以將鉤子插入組織中。樣品因此可以在幾秒鐘內(nèi)安裝好并做好分析準(zhǔn)備。安裝一氣呵成、準(zhǔn)確易操作。

        BioRakes的齒間距從0.7毫米到2.2毫米不等,以適應(yīng)從3到15毫米大小的標(biāo)本。

        BioRake樣品安裝系統(tǒng)

        平衡滑輪樣品安裝系統(tǒng)提供了CellScale在雙軸測(cè)試過(guò)程中確保零剪切應(yīng)力的附著方法。

        兩個(gè)雙端定制縫合鉤被用來(lái)在樣品的每一側(cè)上創(chuàng)建4個(gè)附著點(diǎn)。兩級(jí)不銹鋼滑輪機(jī)構(gòu)確保在測(cè)試過(guò)程中每根縫線(xiàn)保持相同的張力。

        滑輪機(jī)構(gòu)采用磁性安裝方式,便于拆卸清潔,并使BioRake、平衡滑輪和夾具安裝系統(tǒng)之間輕松過(guò)渡。

        平衡滑輪安裝系統(tǒng)

        夾具樣品安裝系統(tǒng)提供了CellScale失敗測(cè)試的附著方法。

        使用十字形試樣可以讓比基礎(chǔ)材料更弱的附著位置遠(yuǎn)離試樣的測(cè)量區(qū)域移動(dòng)。夾具讓樣品可以很容易地加載并且牢固地就位。

        不銹鋼夾緊機(jī)構(gòu)安裝在與其他附著系統(tǒng)相同的支架上,以便在BioRake、平衡滑輪和夾具安裝系統(tǒng)之間快速簡(jiǎn)單的轉(zhuǎn)換。

        還可以進(jìn)行定制夾具設(shè)計(jì),以適應(yīng)您的組織對(duì)夾緊力和夾緊表面的要求。

        夾具安裝系統(tǒng)


        軟件

        BioTester的設(shè)置、操作和數(shù)據(jù)收集軟件模塊讓標(biāo)準(zhǔn)或定制測(cè)試規(guī)程的執(zhí)行變得容易。

        測(cè)試參數(shù)(如位移量、持續(xù)時(shí)間和數(shù)據(jù)/圖像采集速率)以表格格式指定,以便快速訪(fǎng)問(wèn)和修改。位移和受力測(cè)試都可以針對(duì)每個(gè)軸立指定。一旦建立了協(xié)議,就可以使用模板系統(tǒng)快速重新加載所需的測(cè)試參數(shù)。

        軟件界面在測(cè)試設(shè)置期間向用戶(hù)提供實(shí)時(shí)成像和當(dāng)前的力、位置和溫度的信息。在測(cè)試運(yùn)行時(shí),軟件提供實(shí)時(shí)結(jié)果圖形和實(shí)時(shí)視頻饋送,以方便用戶(hù)監(jiān)視測(cè)試進(jìn)度。

        如果詢(xún)問(wèn)使用我們?cè)O(shè)備的用戶(hù),他們會(huì)很快告訴您這個(gè)軟件包是多么的直觀和有用。

         

        BioRake樣品安裝系統(tǒng)


        雙軸測(cè)試的很大一部分是理解和解釋收集到的數(shù)據(jù)。

        BioTester包含一個(gè)圖像分析軟件模塊,可用于查看和分析測(cè)試圖像,提供有價(jià)值的定量和定性信息。該模塊可以用來(lái)導(dǎo)出用于演示目的.avi視頻或帶有數(shù)據(jù)疊加層的圖像。

        BioTester包含一個(gè)高分辨率的相機(jī),在測(cè)試過(guò)程中可以很好地觀察樣品。所收集的圖像(按用戶(hù)指定的頻率)自動(dòng)和力位移數(shù)據(jù)進(jìn)行時(shí)間關(guān)聯(lián),以便軟件模塊可以將鎖有的測(cè)試信息供用戶(hù)選用。

        軟件模塊的圖像跟蹤功能可以快速輕松地分析測(cè)試圖像,以確定樣本表面上一個(gè)或多個(gè)點(diǎn)的平面內(nèi)運(yùn)動(dòng)。這個(gè)跟蹤信息提供了直接的標(biāo)本應(yīng)變測(cè)量,而不依靠由夾點(diǎn)運(yùn)動(dòng)計(jì)算的應(yīng)變。通過(guò)追蹤多點(diǎn)組成的網(wǎng)格,可以研究樣品不同區(qū)域的應(yīng)變。


        平衡滑輪安裝系統(tǒng)


        二、UniVert單軸拉伸、壓縮和扭力測(cè)試分析

        隨時(shí)隨地進(jìn)行您需要的機(jī)械測(cè)試

        UniVert是各種機(jī)械測(cè)試應(yīng)用的里想選擇,它的占地面積小,價(jià)格合理,使用戶(hù)可以隨時(shí)隨地進(jìn)行測(cè)試。易于使用的軟件和可互換的組件使得系統(tǒng)wu需大量的培訓(xùn)或督導(dǎo)即可使用。

        該系統(tǒng)能夠承受高達(dá)200N的拉伸、壓縮和彎曲測(cè)試。各種夾具和固定裝置可用于適應(yīng)不同的標(biāo)本和測(cè)試模式。

        主要?jiǎng)?

        • 小體量即可進(jìn)行質(zhì)量好、性?xún)r(jià)比高的測(cè)試
        • 夾具和加載傳感器的變化易于操作,可以適應(yīng)各種用途。
        • 使用基于圖像的應(yīng)變測(cè)量工具,可實(shí)現(xiàn)高分辨率CCD成像(可選)
        • 功能齊的用戶(hù)界面軟件,可通過(guò)實(shí)時(shí)反饋進(jìn)行簡(jiǎn)單、循環(huán)、松弛和多模式測(cè)試
        參數(shù):
        外形尺寸 22 X 22 X 54cm
        重量 8kg
        力的大小 200N
        可用的加載傳感器 10, 20, 50, 100, 200N
        力的準(zhǔn)確性 加載傳感器容量的0.2%
        大夾點(diǎn)分離 140mm
        大速度 20mm/s
        大循環(huán)頻率 2Hz
        大數(shù)據(jù)速率 100Hz

        三、MicroSquisher壓縮、拉伸、彎曲、壓痕和剪切測(cè)試

        MicroSquisher是一個(gè)微型機(jī)械測(cè)試系統(tǒng),可以做別人所不能做之事。更小的標(biāo)本,更好的解像力,更容易的測(cè)試設(shè)置和j佳的視覺(jué)效果。應(yīng)用包括小組織樣品,水凝膠微球,細(xì)胞球體和工程化組織生長(zhǎng)基質(zhì)。

        主要?jiǎng)?

        • 壓縮、拉伸、彎曲、壓痕和剪切測(cè)試的測(cè)試模式
        • 0.1μm分辨率的高精度壓電執(zhí)行器
        • 解像力降至10nN
        • 高分辨率的CCD成像
        • 集成溫控介質(zhì)浴
        • 功能齊的用戶(hù)界面軟件,可進(jìn)行實(shí)時(shí)反饋的簡(jiǎn)單、循環(huán)、松弛和多模式測(cè)試

        試樣和安裝

        平行板壓縮
        樣品:300μm水凝膠微球(30KPa)
        峰力:20mN

        懸臂彎
        試樣:20μm厚、4mm寬箔帶(70MPa)
        峰力:3mN

        平行板壓縮
        標(biāo)本:直徑2毫米的水凝膠圓柱體(12KPa)
        峰力:20mN

        球形壓痕
        樣品:1.5mm直徑壓頭壓入水凝膠(2KPa)
        峰力: 12mN

        彎曲引起的拉伸
        標(biāo)本:蜘蛛絲
        峰力:2mN

        穿刺附著拉伸
        樣品:3.5mm寬,1.5mm厚的水凝膠(0.5KPa)
        峰力:1.4mN

        四、UStretch用于生物材料的多功能單軸臺(tái)式機(jī)械測(cè)試儀


        UStretch不僅限于大型試樣夾點(diǎn)的干燥垂直測(cè)試。它還可以在溫控或非溫控的介質(zhì)槽內(nèi)進(jìn)行垂直和水平測(cè)試。 他們的系統(tǒng)還有各種各樣的樣品附件,包括螺桿驅(qū)動(dòng)夾具、彈簧夾具和多點(diǎn)刺穿夾具。

        主要?jiǎng)?

        • 帶有直列式加載傳感器的高性能執(zhí)行器
        • 使用基于圖像的應(yīng)變測(cè)量工具,擁有高分辨率CCD成像
        • 有包括專(zhuān)利產(chǎn)品BioRakes在內(nèi)的多種附件選件,可快速可靠地安裝樣品
        • 集成溫控介質(zhì)浴
        • 功能齊的用戶(hù)界面軟件,可通過(guò)實(shí)時(shí)反饋進(jìn)行簡(jiǎn)單、循環(huán)、松弛和多模式測(cè)試

        試樣和安裝

        BioRake

        獲得專(zhuān)利的BioRake附著系統(tǒng)可以使標(biāo)本快速準(zhǔn)確地安裝。

        BioRake樣品安裝系統(tǒng)

        機(jī)械夾點(diǎn)

        機(jī)械夾點(diǎn)附著系統(tǒng)有利于實(shí)現(xiàn)更大的力量和進(jìn)行樣本失敗測(cè)試。

        機(jī)械夾點(diǎn)

        軟件

        集成的軟件可以輕松指定簡(jiǎn)單或復(fù)雜的測(cè)試規(guī)程。測(cè)試規(guī)程可以保存和修改。實(shí)時(shí)的力量和位移圖形有助于測(cè)試驗(yàn)證。

        UStretch軟件與BioTester 軟件構(gòu)建在同一個(gè)平臺(tái)上。 .

        Ustretch 軟件

        成像系統(tǒng)

        可選的成像系統(tǒng)和分析軟件可以對(duì)圖像進(jìn)行分析,以驗(yàn)證樣品的應(yīng)變和應(yīng)變的均勻性。

        Ustretch 軟件

        應(yīng)用文獻(xiàn):


        Instrument

        Year

        Title

        Author

        Link

        BioTester

        2018

        Biaxial mechanical behavior of bovine saphenous venous valve leaflets

        J. Lu, H-Y S. Huang

        View Article

        UniVert

        2018

        Mechanical Strength Of Nafion®/ZrO2 Nano-Composite Membrane

        R. Sigwadi, F. Nemavhola, S. Dhlamini, T. Mokrani

        View Article

        MechanoCulture B1

        2018

        Role of boundary conditions in determining cell alignment in response to stretch

        K. Chen, A. Vigliotti, M. Bacca, R. M. McMeeking, V.S. Dashpande, J.W. Holmes

        View Article

        BioTester

        2018

        Prevalence of Calcification in Human Femoropopliteal Arteries and its Association with Demographics, Risk Factors, and Arterial Stiffness

        A. Kamenskiy, W. Poulson, S. Sim, A. Reilly, J. Luo, J. MacTaggart

        View Article

        BioTester

        2018

        Comparison of corneal biomechanics after myopic small-incision lenticule extraction compared to LASIK: an ex vivo study

        A.J. Kanellopoulos

        View Article

        UniVert

        2018

        Three-Dimensional Printing of Bisphenol A-Free Polycarbonates

        W. Zhu, S-H. Pyo, S. You, C. Yu, J. Alido, J. Liu, Y. Leong, S. Chen

        View Article

        BioTester

        2018

        Dehiscence of patch augmentation of a left-sided atrioventricular valve related to strenuous isometric exercise: Case report and failure analysis

        P.E. Hammer, C.W. Baird, P.J. del Nido, G.R. Marx

        View Article

        BioTester

        2018

        Puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization

        A.A. Ksiazek, L. Frese, P.E. Dijkman, B. Sanders, S. E. Motta, B. Weber, S.P. Hoerstrup

        View Article

        BioTester

        2018

        Biomechanical evaluation of a personalized external aortic root support applied in the Ross procedure

        J. Vastmans, H. Fehervary, P. Verbrugghe, T. Verbelen, E. Vanderveken, J. Vander Sloten, T. Treasure, F. Rega, N. Famaey

        View Article

        BioTester

        2018

        Polydopamine as sizing on carbon fiber surfaces for enhancement of epoxy laminated composites

        W. Han, H-P. Zhang, J. Tavakoli, J. Campbell, Y. Tang

        View Article

        BioTester

        2018

        Comparison of in vivo vs. ex situ obtained material properties of sheep common carotid artery

        M. Smoljkic, P. Verbrugghe, M. Larsson, E. Widman, H. Fehervary, J. D'hooge, J. Vander Sloten, N. Famaey

        View Article

        BioTester

        2018

        Soy Protein/Cellulose Nanofiber Scaffolds Mimicking Skin Extracellular Matrix for Enhanced Wound Healing

        S. Ahn, C.O. Chantre, A.R. Gannon, J.U. Lind, P.H. Campbell, T. Grevesse, B.B. O'Conner, K.K. Parker

        View Article

        BioTester

        2018

        New findings confirm the viscoelastic behaviour of the inter-lamellar matrix of the disc annulus fibrosus in radial and circumferential directions of loading

        J. Tavakoli, J.J. Costi

        View Article

        Ustretch

        2018

        Self-assembled Collagen-Fibrin Hydrogel Reinforces Tissue Engineered Adventitia Vessels Seeded with Human Fibroblasts

        B. Patel, Z. Xu, C. Pinnock, L.S. Kabbani, M.T. Lam

        View Article

        BioTester

        2018

        3D printed, controlled release, tritherapeutic tablet matrix for advanced anti-HIV-1 drug delivery

        M. Siyawamwaya, L.C. du Toit, P. Kumar, Y.E. Choonara, P.P.P.D Kondiah, V. Pillay

        View Article

        MicroSquisher

        2018

        Acrylate-based materials for heart valve scaffold engineering

        R. Santoro, S. Venkateswaran, F. Amandeo, R. Zhang, M. Brioschi, A. Callanan, M. Agrifoglio, C. Banfi, M. Bradley, M. Pesce

        View Article

        BioTester

        2018

        Computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model

        M.Y. Emmert, B.A. Schmitt, S. Loerakker, B. Sanders, H. Spriestersbach,, E.S. Fioretta, L. Bruder, K. Brakmann, S.E. Motta, V. Lintas, P.E. Dijkman, L. Frese, F. Berger, F.P.T. Baaijens, S.P. Hoerstrup

        View Article

        UniVert

        2018

        Fabrication of functionalized citrus pectin/silk fibroin scaffolds for skin tissue engineering.

        S. Tukkan, D. Atila, A. Akdaq, A. Tezcaner

        View Article

        UniVert

        2018

        Rapid continuous 3D printing of customizable peripheral nerve guidance conduits

        W. Zhu, K.R. Tringale, S.A. Woller, S. You, S. Johnson, H. Shen, J. Schimelman, M. Whitney, J. Steinauer, W. Xu, T.L. Yaksh, Q.T. Nguyen, S.Chen

        View Article

        MicroSquisher

        2018

        A Microvascularized Tumor-mimetic Platform for Assessing Anti-cancer Drug Efficacy

        S. Pradhan, A.M. Smith, C.J. Garson, I. Hassani, W.J. Seeto, K. Pant, R.D. Arnold, B. Prabhakarpandian, E.A. Lipke

        View Article

        UniVert

        2017

        A highly deformable conducting traces for printed antennas and interconnects: silver/fluoropolymer composite amalgamated by triethanolamine

        A. Kumar, H. Saghlatoon, T-G. La, M. M. Honari, H. Charaya, H.A. Damis, R. Mirzavand, P. Mousavi, H-J. Chung

        View Article

        MicroSquisher

        2017

        A three-dimensional spheroidal cancer model based on PEG-fibrinogen hydrogel microspheres

        S.Pradhan, J. M. Clary, D. Seliktar, E. A. Lipke

        View Article

        BioTester

        2017

        Biaxial experimental and analytical characterization of a dielectric elastomer

        A. Helal, M. Doumit, R. Shaheen

        View Article

        BioTester

        2017

        Biaxial mechanical properties of bovine jugular venous valve leaflet tissues

        H-Y. S. Huang, J. Lu

        View Article

        BioTester

        2017

        Comparison of Femoropopliteal Artery Stents Under Axial and Radial Compression, Axial Tension, Bending, and Torsion Deformations

        K. Maleckis, P. Deegan, W. Poulson, C. Sievers, A. Desyatova, J. MacTaggart, A. Kamenskiy

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        BioTester

        2017

        Constitutive modeling of human femoropopliteal artery biaxial stiffening due to aging and diabetes

        A. Desyatova, J. MacTaggart, A. Kamenskiy

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        BioTester

        2017

        Constitutive modeling of jugular vein-derived venous valve leaflet tissues

        N. Kaul, H-Y. S. Huang

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        MicroSquisher

        2017

        Decellularized adipose tissue microcarriers as a dynamic culture platform for human adipose-derived stem/stromal cell expansion

        C. Yu, A. Kornmuller, C. Brown, T. Hoare, L.E. Flynn

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        BioTester

        2017

        Design and characterization of a hyperelastic tubular soft composite

        R. Shaheen, M. Doumit, A. Helal

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        MicroSquisher

        2017

        Encapsulation of Equine Endothelial Colony Forming Cells in Highly Uniform, Injectable Hydrogel Microspheres for Local Cell Delivery

        W.J. Seeto, Y. Tian, R.L. Winter, F.J. Caldwell, A.A. Wooldridge, E.A. Lipke

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        BioTester

        2017

        In situ heart valve tissue engineering using a bioresorbable elastomeric implant – From material design to 12 months follow-up in sheep

        J. Kluin, H. Talacua, A.I.P.M. Smits, M. Y. Emmert, M.C.P. Brugmans, E.S. Fioretta, P.E. Dijkman, S.H.M. Sontjens, R.Duijvelshoff, S. Dekker, M.W.J.T. Janssen-van den Broek, V. Lintas, A. Vink, S.P. Hoerstrup, H.M. Janssen, P.Y.W. Dankers, F.P.T. Baaijens, C.V.C. Bouten

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        BioTester

        2017

        JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement

        A.K. Capulli, M.Y. Emmert, F.S. Pasqualini, D. Kehl, E. Caliskan, J.U. Lind, S. P. Sheehy, S.J. Park, S. Ahn, B. Weber, J.A. Goss, S.P Hoerstrup, K.K. Parker

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        BioTester

        2017

        Limb flexion-induced twist and associated intramural stresses in the human femoropopliteal artery

        A. Desyatova, W. Poulson, P. Deegan, C. Lomneth, A. Seas, K. Maleckis, J. MacTaggart, A. Kamenskiy

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        MechanoCulture T6

        2017

        Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation

        S. Wu, Y. Wang, P.N. Streubel, B. Duan

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        MechanoCulture FX

        2017

        Mechanical and signaling roles for keratin intermediate filaments in the assembly and morphogenesis of mesendoderm tissue at gastrulation

        P.R. Sonavane, C. Wang, B. Dzamba, G.F. Weber, A. Periasamy, D.W. DeSimone

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        BioTester

        2017

        Mechanically Robust Electrospun Hydrogel Scaffolds Crosslinked via Supramolecular Interactions

        B.B. Mollet, S. Spaans, P.G. Fard, N.A.M. Bax, C.V.C. Bouten, P.Y.W. Dankers

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        MicroSquisher

        2017

        Microfluidic production of degradable thermoresponsive poly(N-isopropylacrylamide)-based microgels

        D. Sivakumaran, E. Mueller, T. Hoare

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        BioTester

        2017

        Nondestructive mechanical characterization of developing biological tissues using inflation testing

        P.J.A. Oomen, M.A.J. van Kelle, C.W.J. Oomens, C.V.C. Bouten, S. Loerakker

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        BioTester

        2017

        On the influence of wall calcification and intraluminal thrombus on prediction of abdominal aortic aneurysm rupture

        H.E. Barrett, E.M. Cunnane, H. Hidayat, J.M. O'Brien, M.A. Moloney, E.G. Kavanagh, M.T. Walsh

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        BioTester

        2017

        Paraspinal Muscle Passive Stiffness Remodels in Direct Response to Spine Stiffness: A Study Using the ENT1-Deficient Mouse

        K. Gsell, D. Zwambag, D.E. Fournier, C.A. Seguin, S.H.M. Brown

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        MicroSquisher

        2017

        PEG-fibrinogen hydrogels for three-dimensional breast cancer cell culture

        S. Pradhan, I. Hassani, W.J. Seeto, E.A. Lipke

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        MicroSquisher

        2017

        Polysaccharide Hydrogels Support the Long-Term Viability of Encapsulated Human Mesenchymal Stem Cells and Their Ability to Secrete Immunomodulatory Factors

        F. Hached, C. Vinatier, P-G. Pinta, P. Hulin, C. Le Visage, P. Weiss, J. Guicheux, A. Billon-Chabaud, G. Grimandi

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        MicroSquisher

        2017

        Pullulan microbeads/Si-HPMC hydrogel injectable system for the sustained delivery of GDF-5 and TGF-β1: new insight into intervertebral disc regenerative medicine

        N. Henry, J. Clouet, A. Fragale, L.Griveau, C. Chedevile, J. Veziers, P. Weiss, J. Le Bideau, J. Guicheaux, C. Le Visage

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        MicroSquisher

        2017

        Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy

        D. Gillies, W. Gamal, A. Downes, Y. Reinwald, Y. Yang, A.J. El Haj, P.O. Bagnaninchi

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        UniVert

        2017

        Self-reinforcing graphene coatings on 3D printed elastomers for flexible radio frequency antennas and strain sensors

        X. Li, M.M. Honari, Y. Fu, A. Kumar, H. Saghlatoon

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        MechanoCulture FX

        2017

        Tenogenic phenotype maintenance and differentiation using macromolecular crowding and mechanical loading

        D. Gaspar, A. Pandit, D. Zeugolis

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        BioTester

        2017

        Tensile behaviour of individual fibre bundles in the human lumbar anulus fibrosus

        D.T. Pham, J.G. Shapter, J.J. Costi

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        MicroSquisher

        2017

        The physical basis of coordinated tissue spreading in zebrafish gastrulation

        H. Morita, S. Grigolon, M. Bock, S.F.G. Krens, G. Salbreux, C-P. Heisenberg

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        MicroSquisher

        2017

        The role of adhesion junctions in the biomechanical behaviour and osteogenic differentiation of 3D mesenchymal stem cell spheroids

        F.E. Griffin, J. Schiavi, T.C. McDevitt, J.P. McGarry, L.M. McNamara

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        BioTester

        2017

        Urinary Bladder Versus Gastrointestinal Tissue: a Comparative Study of Their Biomechanical Properties for Urinary Tract Reconstruction

        N.F. Davis, J.J.E. Mulvihill, S. Mulay, E.M. Cunnane, D.M. Bolton, M.T. Walsh

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        BioTester

        2016

        A comparison between porcine, ovine, and bovine intervertebral disc anatomy and single lamella annulus fibrosis tensile properties

        L.A. Monaco, S.J. DeWitte-Orr, D.E. Gregory

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        BioTester

        2016

        Acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro

        A.K. Capulli, L.A. MacQueen, B.B. O'Conner, S. Dauth, K.K. Parker

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        MechanoCulture T6

        2016

        Additive manufacturing of a photo-cross-linkable polymer via direct meld electrospinning writing for producing high strength structures

        F. Chen, G. Hochleitner, T. Woodfield, J. Groll, P. Dalton, B.G. Amsden

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        BioTester

        2016

        Age-Dependent Changes in Geometry, Tissue Composition and Mechanical Properties of Fetal to Adult Cryopreserved Human Heart Valves

        D. van Geeman, A.L.F. Soares, P.J.M. Oomen, A. Dressen-Mol, M.W.J.T. Janssen-van den Broek, A.J. van den Bogaerdt, J.J.C. Bogers, M-J. T.H. Goumans, F.P.T. Baaijens, C.V.C. Bouten

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        MicroSquisher

        2016

        An Injectable Hydrogel Prepared Using a PEG/Vitamin E Copolymer Facilitating Aqueous-Driven Gelation

        J. Zhang, B. Muirhead, M. Dodd, L. Liu, N. Mangiacotte, T. Hoare, S. Sheardown

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        BioTester

        2016

        Are adipose-derived stem cells cultivated in human platelet lysate suitable for heart valve tissue engineering

        L. Frese, T. Sasse, B. Sanders, F.P.T. Baaijens, G.M. Beer, S.P. Hoerstrup

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        BioTester

        2016

        Biaxial quantification of deep layer transverse carpal ligament elastic properties by sex and region

        B. Mathers, A. Agur, M. Oliver, K. Gordon

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        BioTester

        2016

        Biomechanical Characterization of Ascending Aortic Aneurysms

        M. Smoljkic, H. Fehervary, P. Van den Bergh, A. Jorge-Penas, L. Kluyns, S. Dymarkowski, P. Verbrugghe, B. Meuris, J. Vander Sloten, N. Famaey

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        BioTester

        2016

        Biomechanical properties and microstructure of heart chambers: a paired comparison study in an ovine model

        S. Javani, M. Gordon, A.N. Azadani

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        BioTester

        2016

        Characterization of three-dimensional anisotropic heart valve tissue mechanical properties using inverse finite element analysis

        M. Abbasi, M.S. Barakat, K. Vanhidkhah, A.N. Azadani

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        BioTester

        2016

        Constitutive description of human femoropopliteal artery aging

        A. Kamenskiy, A. Seas, P. Deegan, W. Poulson, E. Anttila, S. Sim, A. Desyatova, J. MacTaggart

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        MicroSquisher

        2016

        Delivery of Human Adipose Stem Cells Spheroids into Lockyballs

        K.R. Silva, R.A. Rezende, F.D.A.S. Pereira, P. Gruber, M.P. Stuart, A. Ovsianikov, K. Brakke, V. Kasyanov, J.V.L. da Silva, J.M. Granjeiro, L.S. Baptista, V. Mironov

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        BioTester

        2016

        Deposition of a hydrophilic nanocomposite-based coating on a silicone hydrogel through a laser process to minimize UV exposure and bacterial contamination

        G. Huang, W. H. Tse, J. Zhang

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        UniVert

        2016

        Development of an infusion bioreactor for the accelerated preparation of decellularized letal muscle scaffolds

        B. M. Kasukonis, J.T. Kim, T.A. Washington, J.C. Wolchok

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        MicroSquisher

        2016

        Direct Production of Human Cardiac Tissues by Pluripotent Stem Cell Encapsulation in Gelatin Methacryloyl

        P. Kerscher, J.A. Kaczmarek, S.E. Head, M. Brazel, W. Seeto, S. Bhattacharya, J. Kim, V. Suppiramaniam, E.A. Lipke

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        BioTester

        2016

        Improved Geometry of Decellularized Tissue Engineered Heart Valves to Prevent Leaflet Retraction

        B. Sanders, S. Loerakker, E.S. Fioretta, D.J.P. Bax, A. Driessen-Mol, S.P. Hoerstrup, F.P.T. Baaijens

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        BioTester

        2016

        Inflation and bi-axial tensile testing of healthy porcine carotid arteries

        R.W. Boekhoven, M.F.J. Peters, M.C.M. Rutten, M.R. van Sambeek, F.N. van de Vosse, R.G.P Lopata

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        UniVert

        2016

        Material Properties from Air Puff Corneal Deformation by Numerical Simulations on Model Corneas

        N. Bekesi, C. Dorronsoro, A. de la Hoz, S. Marcos

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        MicroSquisher

        2016

        Mineral particles modulate osteo-chondrogenic differentiation of embryonic stem cell aggregates

        Y. Wang, X. Yu, C. Baker, W.L. Murphy, T.C. McDevitt

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        BioTester

        2016

        Modulation of collaen fiber orientation by strain-controlled enzymatic degradation

        S. Ghazanfari, A. Dressen-Mol, C.V.C. Bouten, F.P.T. Baaijens

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        BioTester

        2016

        Nanocomposited coatings produced by laser-assisted process to prevent silicone hydrogels from protein fouling and bacterial contamination

        G. Huang, Y. Chen, J. Zhang

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        BioTester

        2016

        Patient Specific Vascular Benchtop Models for Development and Validation of Medical Devices for Minimally Invasive Procedures

        M. Kvasnytsia, N. Famaey, M. Bohm, E. Verhoelst

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        BioTester

        2016

        Peak stress in the annulus fibrosis under cyclic biaxial tensile loading

        C.E. Gooyers, J.P. Callaghan

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        MicroSquisher

        2016

        PEG-fibrinogen Hydrogels for Three-dimensional Breast Cancer Cell Culture

        S. Pradhan, I. Hassani, W.J. Seeto, E. A. Lipke

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        BioTester

        2016

        Phototactic guidance of a tissue-engineered soft-robotic ray

        S-J. Park, M. Gazzola, K.S. Park, S. Park, V. Di Santo, E.L Blevins, J.U. Lind, P.H. Campbell, S. Dauth, K.K. Parker

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        BioTester

        2016

        Planar biaxial testing of heart valve cusp replacement biomaterials: Experiments, theory and material constants

        M.R. Labrosse, R. Jafar, J.Ngu, M. Boodhwani

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        BioTester

        2016

        Planar biaxial testing of soft biological tissue using rakes: A critical analysis of protocol and fitting process

        H. Fehervary, M. Smoljkic, J.Vander Sloten, N. Famaey

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        BioTester

        2016

        Production of Synthetic, Para-Aramid and Biopolymer Nanofibers by Immersion Rotary Jet-Spinning

        G.M. Gonzalez, L.A. MacQueen, J.U. Lind, S.A. Fitzgibbons, C. O. Chantre, I. Huggler, H.M. Golecki, J.A. Goss, K.K. Parker

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        BioTester

        2016

        Quantification of Coupled Stiffness and Fiber Orientation Remodeling in Hypertensive Rat Right-Ventricular Myocardium Using 3D Ultrasound Speckle Tracking with Biaxial Testing

        D.W. Park, A. Sebastiani, C.H. Yap, M.A. Simon, K. Kim

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        MicroSquisher

        2016

        Reactive eletrospinning of degradable poly(oligoethylene glycol methacrylate)-based nanofibrous hydrogel networks

        F. Xu, H. Sheardown, T. Hoare

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        BioTester

        2016

        The aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae

        D.M. Stewart, L.A. Monaco, D.E. Gregory

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        BioTester

        2016

        The choice of a constitutive formulation for modeling limb flexion-induced deformations and stresses in the human femoropopliteal arteries of different ages

        A. Desyatova, J. MacTaggart, W. Poulson, P. Deegan, C. Lomneth, A. Sandip, A. Kamenskiy

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        BioTester

        2016

        The Effect of Local Hydration Environment on the Mechanical Properties and Unloaded Temporal Changes of Isolated Porcine Annular Samples

        K.M. Gruevski, C.E. Gooyers, T. Karakolis, J.P. Callaghan

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        UniVert

        2016

        The global mechanical properties and multi-scale failure mechanics of heterogeneous human stratum corneum

        X. Liu, J. Cleary, G.K. German

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        BioTester

        2015

        Adipose derived tissue engineered heart valve

        L. Frese, B. Sanders, G.M. Beer, B. Weber, A. Driessen-Mol, F.P.T. Baaijens, S.P. Hoerstrup

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        BioTester

        2015

        Biaxial stress relaxation of semilunar heart valve leaflets during simulated collagen catabolism: effects of collagenase concentration and equibiaxial strain state

        S. Huang, H.-Y. S. Huang

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        BioTester

        2015

        Building a better infarct: Modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction

        A.P. Voorhees, K.Y. DeLeon-Pennell, Y. Ma, G. V. Halade, A. Yabluchanskiy, R. Padmanabhan, E. Flynn, C.A. Cates, M.L. Lindsey, H.-C. Han

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        MicroSquisher

        2015

        Burr-like, laser-made 3D microscaffolds for tissue spheroid encagement

        P. Danilevicius, R.A. Rezende, F.D.A.S. Pereira, A. Selimis, V. Kasyanov, P.Y. Noritomi, J.V.L. da Silva, M.Chatzinikolaidou, M. Farsari, V. Mironov

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        BioTester

        2015

        Corneal collagen cross-linking combined with simulation of femtosecond laser-assisted refractive lens extraction: an ex vivo biomechanical effect evaluation

        A.J. Kanellopoulos, M.A. Kontos, S. Chen, G. Asimellis

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        BioTester

        2015

        Development of a biological scaffold engineered using the extracellular matrix secreted by letal muscle cells

        S.A. Hurd, N.M. Bhatti, A.M. Walker, B.M. Kasukonis, J.C. Wolchok

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        UniVert

        2015

        Development of a biological scaffold engineered using the extracellular matrix secreted by letal muscle cells

        S. A. Hurd, N.M. Bhatti, A.M. Walker, B.M. Kasukonis, J.C. Wolchok

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        BioTester

        2015

        Development of non-cell adhesive vascular grafts using supramolecular building blocks

        G. C. van Almen, H. Talacua, B.D. Ippel, B.B. Mollet, M. Ramaekers, M. Simonet, A.I.P.M. Smits, C.V.C. Bouten, J. Kluin, P.Y.W. Dankers

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        BioTester

        2015

        High-irradiance CXL combined with myopic LASIK: flap and residual stroma biomechanical properties studied ex-vivo

        A.J. Kanellopoulos, G. Asimellis, B.Salvador-Culla, J. Chodosh, J.B. Ciolino

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        UniVert

        2015

        High-irradiance CXL combined with myopic LASIK: flap and residual stroma biomechanical properties studied ex-vivo

        A. J. Kanelloploulos, G. Asimellis, B. Salvador-Culla, J. Chodosh, J.B. Ciolino

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        BioTester

        2015

        Improved geometry of decellularized tissue engineered heart valves to prevent leaflet retraction

        B. Sanders, S. Loerakker, E.S. Fioretta, D.J.P. Bax, A. Driessen-Mol, S.P.Hoerstrup, F.P.T Baaijens

        View Article

        BioTester

        2015

        Leaflet stress and strain distributions following incomplete transcatheter aortic valve expansion

        M. Abbasi, A.N. Azadani

        View Article

        BioTester

        2015

        Methods for using 3-D ultrasound speckle tracking in biaxial mechanical testing of biological tissue samples

        C.H. Yap, D.W. Park, D. Dutta, M. Simon, K. Kim

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        BioTester

        2015

        Nanocomposite silicone hydrogels with a laser-assisted surface modification for inhibiting the growth of baterial biofilm

        P. Yin, G.B. Huang, W.H. Tse, Y.G. Bao, J. Denstedt, J. Zhang

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        BioTester

        2015

        Regional and depth variability of porcine meniscal mechanical properties through biaxial testing

        A. Kahlon, M.B. Hurtig, K.D. Gordon

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        BioTester

        2015

        Superior tissue evolution in slow degrading scaffolds for valvular tissue engineering

        M. Brugmans, S. Soekhradj-Soechit, D. van Geemen, M.A.J. Cox, C. Bouten, F.P.T. Baaijens, A. Driessen-Mol

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        BioTester

        2015

        The Biomechanics of Eyelid Tarsus Tissue

        M.T. Sun, D. Pham, A.J. O'Conner, J. Wood, R. Casson, D. Selva, J.J. Costi

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        BioTester

        2014

        Cardiac Function of the Naked Mole-Rat: Echophysiological Responses to Working Underground

        K.M. Grimes, A. Voorhees, Y.A. Chiao, H-C. Han, M.L. Lindsey, R. Buffenstein

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        BioTester

        2014

        Directional Biomechanical Properties of Porcine Skin Tissue

        H-Y. Huang, S. Huang, C.P. Frazier, P.M. Prim, O. Harrysson

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        UniVert

        2014

        Intrastromal Application of Riboflavin for Corneal Crosslinking

        T.G. Seiler, I. Fischinger, T. Senfft, G. Schmidinger, T. Seiler

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        MicroSquisher

        2014

        Mesenchymal morphogenesis of embryonic stem cells dynamically modulates the biophysical microtissue niche

        M.A. Kinney, R.Saeed, T.C. McDevitt

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        BioTester

        2014

        Modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues

        G. Argento, N. de Jonge, S.H.M. Sontjens, C.W.J. Oomens, C.V.C. Bouten, F.P.T. Baaijens

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        BioTester

        2014

        Should a native depth-dependent distribution of human meniscus constitutive components be considered in FEA-models of the knee joint?

        J.M. Parraga Quiroga, P. Emmans, W. Wilson, K. Ito, C.C. van Donkelaar

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        BioTester

        2014

        Strain-dependent modulation of macrophage polarization within scaffolds

        V. Ballotta, A. Dressen-Mol, C.V.C. Bouten, F.P.T. Baaijens

        View Article

        BioTester

        2014

        Structural and mechanical adaptations of right ventrical free wall myocardium to pressure overload

        M.R. Hill, M.A. Simon, D. Valdez-Jasso, H.C. Champion, M.S. Sacks

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        BioTester

        2014

        The biaxial biomechanical behavior of adominal aortic aneurysm tissue

        S.A. O'Leary, D.A. Healey, E.G. Kavanagh, M.T. Walsh, T.M. McGloughling, B.J. Doyle

        View Article

        BioTester

        2014

        The biaxial mechanical behaviour of abdominal aortic aneurysm intraluminal thrombus: Classification of morphology and the determination of layer and region specific properties

        S.A. O'Leary, E.G. Kavanagh, P.A. Grace, T.M. McGloughlin, B.J. Doyle

        View Article

        BioTester

        2014

        The impact of long term freezing on the mechanical properties of porcine aortic tissue

        S. O'Leary, B. Doyle, T. McGloughlin

        View Article

        BioTester

        2014

        Vascular Elastography: A Validation Study

        R.G.P. Lopata, M.F.J. Peters, J. Nijs, C.W. Oomens, M.C.M. Rutten, F.N. van de Vosse

        View Article

        BioTester

        2013

        A Nanocomposite Contact Lens for the Delivery of Hydrophilic Protein Drugs

        J. Zhang, R. Bi, W. Hodge, P. Yin, W.H. Tse

        View Article

        MicroSquisher

        2013

        Alginate Encapsulation Parameters Influence the Differentiation of Microencapsulated Embryonic Stem Cell Aggregates

        Wilson, J.L., Ali Naijia, M., Saeed, R., McDevitt, T.C.

        View Article

        BioTester

        2013

        Comparison of methods used to measure the thickness of soft tissues and their influence on the evaluation of tensile stress

        S.A. O'Leary, B.J. Doyle, T.M. McGloughlin

        View Article

        BioTester

        2013

        Corneal resistance to shear force after UVA-riboflavin cross-linking

        A.P. Sondergaard, A. Ivarsen, J. Hjortdal

        View Article

        BioTester

        2013

        In vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells

        B. Weber, D. Kehl, U. Bleul, S. Sammut, L. Frese, A. Ksiazek, L Behr, J. Achermann, G. Stranzinger, J. Robert, B. Sanders, M. Sidler, C.E. Brokopp, S.T. Proulx, T. Frauenfelder, R. Schoenauer, M.Y.Emmert, V. Falk, S.P.Herstrup

        View Article

        BioTester

        2013

        Mechanical Analysis of Ovine and Pediatric Pulmonary Artery for Heart Valve Stent Design

        M.S. Cabrera, C.W.J. Oomens, C.V.C. Bouten, A.J.J.C. Bogers, S.P. Hoerstrup, F.P.T. Baaijens

        View Article

        BioTester

        2013

        Mechanics of the pulmonary valve in the aortic position

        A.L.F. Soares, D. van Geeman, A.J. van den Bogaerdt, C.W.J. Oomens, C.V.C. Bouten, F.P.T. Baaijens

        View Article

        BioTester

        2013

        Reduction of Stromal Swelling Pressure after UVA-Riboflavin Cross-Linking

        A.P. Sondergaard, A. Ivarsen, J. Hjortdal

        View Article

        BioTester

        2012

        A Murine Experimental Model for the Mechanical Behavior of Viable Right-Ventricular Myocardium

        D. Valdez-Jasso, M.A. Simon, H.C. Champion, M.S. Sacks

        View Article

        BioTester

        2012

        An Examination of the Mechanical Properties of the Annulus Fibrosus: The Effect of Vibration on the Intra-lamellar Matrix Strength

        Diane Gregory, J. Callaghan

        View Article

        BioTester

        2012

        Application of Simple Biomechanical and Biochemical Tests to Heart Valve Leaflets: Implications for Heart Valve Characterization and Tissue Engineering

        H-Y. Huang, B.N. Balhouse, S. Huang

        View Article

        BioTester

        2012

        Biomechanical Properties of the Transverse Carpal Ligament Under Biaxial Strain

        Michael Holmes, S. Howarth, J. Callaghan, P. Keir

        View Article

        BioTester

        2012

        Multi-Scale Mechanical Characterization of Scaffolds for Heart Valve Tissue Engineering

        G. Argento, M. Simonet, C.W.J. Oomens, F.P.T. Baaijens

        View Article

        MicroSquisher

        2012

        Stiffening of Human Mesenchymal Stem Cell Spheroid Mircoenvironments Induced By Incorporation of Gelatin Microparticles

        P. R. Baraniak, M.T. Cooke, R. Saeed, M.A. Kinney, K.M. Fridley, T.C. mcDevitt

        View Article

        BioTester

        2011

        A Comparison of Uniaxial and Biaxial Mechanical Properties of the Annulus Fibrosus: A Porcine Model

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